UK ophthalmologists lead treatment of wet AMD patients

Sheffield Teaching Hospitals NHS Foundation Trust achieves treatment milestone with Oraya Therapy

Christopher Brand is one of the leading users of Oraya Therapy

Oraya Therapeutics has announced that UK ophthalmologists are the leading adopters of Oraya Therapy for the treatment of wet age-related macular degeneration (AMD), two years after the treatment was first introduced in the country.

Sheffield Teaching Hospitals NHS Foundation Trust alone has treated more than 150 patients in the year since the service was commissioned, with other NHS and private centres in England also increasing their use of Oraya Therapy.

Oraya Therapy was introduced first in the UK, followed by Switzerland and Germany. The therapy is intended as a one-time, non-invasive treatment that maintains vision with fewer anti-vascular endothelial growth factor (anti-VEGF) injections into the eye.

“We need additional therapies to anti-VEGF injections in treating wet AMD,” said Christopher Brand, consultant ophthalmologist at Royal Hallamshire Hospital in Sheffield.

In addition to benefiting patients, Oraya Therapy can reduce the burden of care in our clinics and hospitals as the number of wet AMD patients increases

“With the availability of Oraya Therapy, we’ve been able to offer patients an adjunctive treatment that has been shown in a clinical study to reduce the number of injections required and to potentially enhance the patient's quality of life. In addition to benefiting patients, Oraya Therapy can reduce the burden of care in our clinics and hospitals as the number of wet AMD patients increases."

Jim Taylor, president and chief executive of Oraya Therapeutics, added: “We are pleased to see the integration of Oraya Therapy into standard clinical care, and look forward to establishing additional treatment centres in the coming months.”

Oraya Therapy is already available at four sites in the UK: Sheffield Teaching Hospitals NHS Foundation Trust, Heart of England NHS Foundation Trust, Optegra Manchester Eye Hospital, and Kent Institute of Medicine and Surgery (KIMS). Outside of the UK it is available at four treatment centres in Germany and one location in Switzerland, with an equal number in the active planning pipeline.

Oraya Therapy is a non-invasive treatment for patients with wet AMD. It delivers highly-targeted, low-energy X-rays to the diseased area of the eye and is intended as a one-time outpatient procedure. The therapy has been shown in a randomised, sham-controlled, double-blind clinical study to reduce the required number of anti-VEGF injections into the eye whilst maintaining vision, and requires no post-treatment recovery period before patients can resume normal activity.

Wet AMD affects 250,000 people in the UK alone, and is the leading cause of blindness in people aged over 65 in the western world. If left untreated, it can quickly lead to loss of central vision.

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